neweastbio@126.com
PRODUCT CENTER
價(jià)格 | ¥4800.00 |
品牌 | NewEast Biosciences |
產(chǎn)地 | 中國 武漢 |
貨號 | 26912 |
規(guī)格 | 30μl |
說明書 | 說明書下載 |
Active Rap1-GTP [26912]
[30 µL]
Catalog Number: 26912 |
Gene Symbol: RAP1 |
Description: Anti Active Rap1 Mouse Monoclonal Antibody |
Background: Small GTPases are a super-family of cellular signaling regulators. Rap family members (Rap1A, Rap1B, Rap2A, Rap2B, and Rap2C) are Ras-like GTPases that regulate cell proliferation, differentiation, apoptosis and adhesion mechanisms. Rap1 (Ras-proximate-1) regulates apoptosis through interaction with two MAP3K effectors of the MEK/ERK MAP-kinase pathway, Raf-1 and B-Raf. Rap1 regulates cell adhesion mechanisms through effector molecules such as the integrins and cadherins. |
Immunogen: Recombinant full length protein of active Rap1. |
Applications: IP, IHC |
Recommended Dilutions: 1 μg for 1~2 mg total cellular proteins for IP 1:100 dilution for IHC |
Concentration: 1 mg/ml |
Host: mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG |
Purity: Purified from ascites |
Storage buffer: |
Preservative: no |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Anti-active Rap1 antibody recognizes active Rap1 of vertebrates. |
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
Immunoprecipitation/Western blot: |
Rap1 activation assay. Purified Rap1 proteins were immunoprecipitated after treated with GDP (lane 1) or GTPγS (lane 2). Immunoprecipitation was done with the anti-active Rap1 monoclonal antibody (Cat. No. 26912). Immunoblot was with an anti-Rap1 polyclonal antibody (Cat. No. 21104). |
Related Products | |||
Catalog# | Name | Size | Price |
26912 | Active Rap1 GTP Monoclonal Antibody | 30 μL | ¥4800 |
81401 | Rap1 Activation Assay Kit | 20 assays | ¥6800 |
Publications: |
1. Rap1 GTPase Activation and Barrier Enhancement in RPE Inhibits Choroidal Neovascularization In Vivo PLoS One. 2013 Sep 10;8(9):e73070 |
發(fā)表時間:2013-06-04
名稱/貨號:Anti- Active Rap1 Mouse Monoclonal Antibody/26912
影響因子:Scientific Reports IF=4.6
應(yīng)用范圍:ICC
種屬:hippocampi
發(fā)表時間:2013-06-04
名稱/貨號:Anti- Active Rap1 Mouse Monoclonal Antibody/26912
影響因子:The Journal of Physiology IF=5.5
應(yīng)用范圍:IHC
種屬:Mouse
發(fā)表時間:2021-06-24
名稱/貨號:Anti- Active Rap1 Mouse Monoclonal Antibody/26912
影響因子:The FASEB Journal IF=4.8
應(yīng)用范圍:IHC
種屬:Human
發(fā)表時間:2023-03-09
名稱/貨號:Rap1 Pulldown Activation Assay Kit/81401
影響因子:Cell & Bioscience IF=7.5
應(yīng)用范圍:IP-WB
種屬:Human
發(fā)表時間:2024-03-14
名稱/貨號:Rap1 Pulldown Activation Assay Kit/81401
影響因子:Advanced Science IF=15.1
應(yīng)用范圍:IP-WB
種屬:Mouse
技術(shù)支持:優(yōu)狐