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Anti- Active Rab7 Mouse Monoclonal Antibody

價(jià)格¥4800.00
品牌NewEast Biosciences   
產(chǎn)地中國(guó) 武漢
貨號(hào)26923
規(guī)格30μl
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  • Active Rab7 GTP [26923]
    [30 µL]

     

    Catalog Number:  26923
    Gene Symbol:  RAB7
    Description:   Anti Active Rab7 Mouse Monoclonal Antibody
    Background:   Rab7 belongs to the Rab family of small GTPases. Rab7 is located in the late endosome, lysosome, cytoplasmic vesicle, phagosome and melanosome. It is involved in the late endocytic transport and contributes to the maturation of phagosomes.
    Immunogen:   Recombinant full length protein of active Rab7
    Applications:   IP, IHC, IF
    Recommended Dilutions:   
    1 µg for ~2 mg total cellular proteins for IP 
    1:100 dilution for IHC, IF
    Concentration:   1 mg/ml
    Host:   mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   IgG
    Purity:   Purified from ascites
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Anti active Rab7 antibody recognizes active Rab7 proteins of vertebrates.
    Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles
     
    Immunoprecipitation/Western blot:  
    Rab7 activation assay. Purified full-length Rab7 proteins were immunoprecipitated after treated with GDP (lane 1) orGTPγS (lane 2). Immunoprecipitation was done with the anti active Rab7 monoclonal antibody (Cat. No. 26923). Immunoblot was with an anti Rab7 polyclonal antibody (Cat. No. 21069).

     

    Related Products
    Catalog# Name Size Price
    82501 Rab7 Activation Assay Kit  20 assays  ¥6800 
    26923 Active Rab7 GTP Monoclonal Antibody  30 μL  ¥4800 
    21069 Anti Rab7A Rabbit Polyclonal Antibody  100 μL  ¥2600

     

     

    Publications:
    1.  VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors
        Hepatology Volume 61, Issue 1, pages 361–374, January 2015
    2.  Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance
        Endocrinology. 2014 Sep;155(9):3315-28

     

     

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